Acremine F is a fungal metabolite that has been found in Acremonium.

8-Oxo-dATP lithium, as an oxidized purine nucleoside triphosphate, is hydrolyzed by MTH1 into monophosphates, thereby preventing errors caused by its misincorporation during DNA replication or transcription.

8-Bromo-2'-deoxy-ATP (8-Bromo-dATP) tetrasodium is a derivative of the nucleoside triphosphate 2'-Deoxyadenosine-5'-triphosphate (dATP).

8-Aminoguanine is a endogenous purine. 8-Aminoguanine inhibits PNPase (purine nucleoside phosphorylase). 8-Aminoguanine induces diuresis/natriuresis/glucosuria.

6-Hydroxy bexarotene is the main circulating metabolite of bexarotene, found in rats, dogs, and humans. Compared to the parent compound, 6-hydroxy-bexarotene shows a significantly reduced ability to bind to retinoid receptors and exhibits very minimal activity in activating retinoic acid receptors.

5-Androstenetriol is a systemic radiation protector that can boost the host's immunity, leading to increased resistance to infections. 5-Androstenetriol can raise levels of IL-2, IL-3, and IFN, while countering the immunosuppressive effects of Hydrocortisone.

4-Hydroxyphenylpropionylglycine is a metabolite of the conditionally essential amino acid Tyrosine.

3-Oxochenodeoxycholic acid is an endogenous metabolite that can be found in feces. 3-Oxochenodeoxycholic acid can serve as an indicator for the diagnosis of certain diseases, such as COVID-19.

3-Methyl-2-butenal (3-Methylbut-2-en-1-al) can be isolated from hops.

3-Hydroxylidocaine is the major metabolite of Lidocaine in rats and sheep.

3-Epideoxycholic acid is the microbial metabolite of Deoxycholic acid. 3-Epideoxycholic acid targets FXR of dendritic cells, reduces their immunostimulatory properties, promotes the generation of Treg cells, and exhibits anti-inflammatory activity. 3-Epideoxycholic acid promotes the growth of bacteria Bacteroides.

3-cis-Hydroxyglibenclamide is the metabolism of Glibenclamid.

1-Monoarachidin is a fatty acid that is derived from 2-arachidonoylglycerol.

19(R)-Hydroxy prostaglandin F1α is an ω-1 hydroxylase metabolite of PGF1α.

17(R)-Resolvin D1 methyl ester is the methyl ester of Resolvin D1 (RvD1) induced by Aspirin with the 17R epimer (AT-RvD1). RvD is a regulator of transendothelial migration of human polymorphonuclear leukocytes and an anti-inflammatory agent. The 17R-trihydroxy-4Z of RvD1 also blocks transendothelial migration of human neutrophils (EC50 approximately 30 nM). AT-RvD1 is an effective form that protects against the rapid inactivation of Resolvin D1.

16-Carboxymitragynine is a metabolite of mitragynine.

15-keto Prostaglandin F1α (15-keto PGF1α) is a prostaglandin F1α metabolite. 15-keto Prostaglandin F1α (15-keto PGF1α) is an effective substrate for PGR-2. 15-keto Prostaglandin F1α (15-keto PGF1α) can be used to study physiological processes such as prostaglandin metabolism and lipogenesis.

14,15-Leukotriene D4 (14,15-LTD4) is a leukotriene that producted by eosinophils with Arachidonic acid that can be used as a negative control for the protein-protein inhibition activity of UNC6934.

13,14-Dihydro-15-keto-PGE2 participates in Bifidobacterium animalis F1-7 to alleviate opioid-induced constipation by 5-HT pathway.

1,3-Dipalmitoyl-2-stearoyl glycerol (1,3-Palmitin-2-stearin) is a triacylglycerol in which palmitic acid is located at the sn-1 and sn-3 positions, and stearic acid is at the sn-2 position. The levels of 1,3-Dipalmitoyl-2-stearoyl glycerol are associated with energy depletion caused by reduced food intake in rats.

1,3-Capryloyl-2-oleoylglycerol is a triglyceride. 1,3-Capryloyl-2-oleoylglycerol has its hydroxyl groups at the 1 and 3 positions of glycerol acylated by Caprylic acid and the hydroxyl group at the 2 position acylated by Oleic acid in its molecule.

1,2-Stearin-3-linolein is a triacylglycerol. 1,2-Stearin-3-linolein has Stearic acid at sn-1 and sn-2 positions, and contains Linoleic acid at sn-3 position.

1,2,3-tri-γ-Linolenoyl glycerol is a triacylglycerol with γ-linolenic acid attached to the three esterification sites (1, 2 and 3) of glycerol.

(5α)-3,6-Dioxocholan-24-oic acid is a secondary bile acid.

(±)-Δ7-Mesembrenone is a mesembrine-type alkaloid which can be extracted from various Sceletium.

(±)7(S),8(R)-EDT is an isomer of 7,8-EDT.

(+/-)-Adomeglivant ((+/-)-LY2409021) is a potent and selective glucagon receptor antagonist with hypoglycemic activity. (+/-)-Adomeglivant is effective in lowering blood sugar levels in both healthy people and people with type 2 diabetes. (+/-)-Adomeglivant is well tolerated by glucagon signaling blockade in patients with type 2 diabetes and significantly reduces fasting and postprandial blood glucose with a concomitant reversible elevation of aminotransferases. Glucagon signaling inhibition by (+/-)-Adomeglivant is a promising potential inhibitory approach for patients with type 2 diabetes and warrants further evaluation of its benefits and risks in longer clinical trials.

Piribedil N-oxide is a metabolite of the dopamine receptor agonist Piribedil.

N-Desmethyl rosiglitazone (SB 237216) is a metabolite of Rosiglitazone, generated through demethylation by the cytochrome P450 enzyme system in liver microsomes. It retains partial PPARγ agonist activity and supports studies on the metabolism and pharmacokinetics of Rosiglitazone.

Desmethyl mirtazapine (Normirtazapine) hydrochloride is a metabolite of Mirtazapine. Mirtazapine is a potent and orally active noradrenergic and specific serotonergic antidepressant (NaSSA) agent.