Novel hypoxia inducible factor hydroxylase modulator

Novel hypoxia inducible factor hydroxylase modulator

Novel HIF-1alpha-p300 Protein Protein Interaction inhibitor

Novel HIF-1alpha inhibitor

CNS active anticonvulsant and ultra-short acting hypnotic

Pentapeptide sequences of hIAPP, being sufficient for the formation of beta-sheet-containing amyloid fibrils and self-assemble laterally into unusually broad ribbons

Hexapeptide sequences of hIAPP, being sufficient for the formation of beta-sheet-containing amyloid fibrils and coiling around each other in a typical amyloid fibril morphology

Potent inhibitor of multidrug-resistant human immunodeficiency virus-1 (HIV-1)

Potent non-nucleoside inhibitor of drug-resistant human immunodeficiency virus (HIV)

Non-nucleoside reverse transcriptase inhibitor

Positive allosteric modulator at the barbiturate/picrotoxin site of the GABAA receptor

Novel sulfur-triazole exchange (SuTEx) covalent probe with ~5-fold enhanced chemoselectivity for tyrosines over other nucleophilic amino acids

Fragment 177-191 of human growth hormone, regulating fat metabolism but without the adverse effects on blood sugar or growth, stimulating lipolysis (the breakdown or destruction of fat) and inhibiting lipogenesis (the transformation of nonfat food materia

Novel type II inhibitor of wild-type and gatekeeper mutants of BCR-ABL, PDGFRalpha, Kit, and Src kinases

Insulin-regulated aminopeptidase (IRAP) inhibitor, mprovin memory in control and memory-deficient mice models

Potent inducer of oxidative stress as well as cell cycle arrest in the S-phase, significantly decreasing intracellular ATP level

Novel potent inducer of hexamethylene bis-acetamide inducible protein 1 (HEXIM1)

Novel inhibitor of the phosphorylation of DRP1, stimulating a phenotype suggestive of respiration through mitochondrial normalization and demonstrating activity in Vemurafenib-resistant melanoma in vivo

Novel orally bioavailable, non-peptide thrombopoietin (TPO) receptor agonist

Novel TGF-β Signaling Inhibitor

Novel LsrK inhibitor (ID 50 119 μM) agaist antimicrobial resistance (AMR)

Novel inhibitor of Tau aggregation against Tau-related neurodegenerative diseases including Alzheimer's disease (AD)

Master regulator of iron homeostasis, contributing to Swedish mutant APP-induced osteoclastogenesis and trabecular bone loss

Heparin derivative for treatment of thrombotic diseases

Heparan sulfate antagonist

The biosynthetic precursor of gossypol

Cytotoxic peptide, inducing mitotic arrest and abnormal spindle formation

Inhibitor of interleukin-1β-induced MIP-1β production

Natural anti-inflammatory and anti-cancer agent

Anti-inflammatory and anti-cancer agent, disrupting the cooperation of CCAAT-box/enhancer-binding protein beta (C/EBPß) and co-activator p300