Novel selective non-imidazole histamine H 3 receptor antagonist

Novel competitive inhibitor of rTbIPMK with respect to Ins(1,4,5)P3

Novel potent, metabolically stable and centrally penetrant PPARγ partial agonist

Novel inhibitor of EPHX2 (epoxide hydrolase 2, alias soluble epoxide hydrolase or sEH), up-regulating cytoprotective genes and down-regulating proinflammatory cytokine production

Potent and selective H3 histamine receptor inverse agonist

Potent non-cytotoxic inhinitor of Mycobacterium tuberculosis H37Rv

Novel noncompetitive inhibitor of rTbIPMK

Potent non-cytotoxic inhinitor of Mycobacterium tuberculosis H37Rv

Potent non-cytotoxic inhinitor of Mycobacterium tuberculosis H37Rv

Novel dual inhibitor of BPTF and Brd4

Novel specific P2X(7) receptor antagonist

Non-peptidic snail toxin; Activator of the Kv1.1 potassium ion channel

Novel allosteric inhibitor of human immunodeficiency virus (HIV) integrase, blocking viral replication and abnormal multimerization involving specific protein domains

Novel selective inhibitor of MmpL3 mutation

Potent and selective GPR119 agonist

Novel inhibitor of polo-like kinase

Novel inhibitor of polo-like kinase

Potent inhibitor of AKT kinase, showing activity against auxotrophic M. tuberculosis and being potentiated with meropenem

Novel dual H1 and H3 receptor antagonist with a long duration of action

Potent inhibitor of AKT kinase

Novel potent EchA6 inhibitor

Novel allosteric HIV-1 integrase (IN) inhibitor, disrupting formation of mature HIV particles

Glutamate receptor antagonist and radical scavenging agent

Novel high potent and selective stabilizer of the MYC G-quadruplex (G4)

Potent and selective inhibitor of HIV-1 protease, effectively inhibiting protease mutants with amino acid insertions, also inhibiting major aspartyl peptidase 1 (May1), a secreted Cryptococcus neoformans protease

Novel oral prodrug of GS-441524, inhibiting SARS-CoV-2, including variants of concern (VOC) in cell culture and human airway epithelium organoids

Novel Inhibitor of Hepatitis C Viral Infectivity

Novel potent inhibitor of feline infectious peritonitis (FIP) virus in tissue culture and experimental cat infection studies

Novel allosteric inhibitor of respiratory syncytial virus (RSV)

Novel β-Secretase BACE1 Inhibitor, reversing memory impairments and rescuing age-related cognitive decline