Antipsychotic agent, blocking postsynaptic dopamine D2 receptors in the limbic, cortical system and basal ganglia

Antipsychotic agent, blocking postsynaptic dopamine D2 receptors in the limbic, cortical system and basal ganglia

Atypical antipsychotic agent and ligand for the serotonin receptors 5-HT6/5-HT7

Fungicide for the control of fungal diseases such as early blight, late blight, leaf spots, leaf rust, and Rhizoctonia solani.

Novel potent neuroprotective agent for treatment of Alzheimer's disease (AD), targeting NMDA receptor

Novel potent neuroprotective agent for treatment of Alzheimer's disease (AD), targeting NMDA receptor

Monoamine oxidase A (MAO-A) specific inhibitor

Green-fluorescent intracellular calcium indicator

Green-fluorescent intracellular calcium indicator

Herbicide, inhibiting very-long-chain fatty acid elongase (VLCFAE) synthesis

Novel photolabile NO donor

The first phthalic acid diamide insecticide, impairs neuronal calcium signalling in the honey bees antennae

Novel STAT3 activation inhibitor, induces cell cycle arrest and apoptosis in cancer cells harboring constitutively-active STAT3

Novel selective and efficacious inhibitor of FLT3 mutations

Novel potent ATP-competitive inhibitor of Flt3

Novel FLT3 inhibitor, displaying potent inhibitory activity against the FLT3-ITD mutant (IC 50 = 0.8 nM) and good selectivity over c-KIT kinase (over 500-fold), selectively inhibiting the proliferation of FLT3-ITD-positive AML cell lines MV4-11 (IC 50 = 2

Tumour hypoxia probe

Inhibitor of STAT3 phosphorylation and apoptotic promoter of human renal cell carcinoma and melanoma cell lines

Curcumin analogue, exhibiting enhanced growth-suppressive activity and inhibiting AKT and signal transducer and activator of transcription 3 phosphorylation in breast and prostate cancer cells

Curcumin analogue, exhibiting enhanced growth-suppressive activity and inhibiting AKT and signal transducer and activator of transcription 3 phosphorylation in breast and prostate cancer cells

Novel inhibitor of general secretion in early stage; FLI-06 analogue twice as active as FLI-06

Novel, potent, orally active, and nonsteroidal farnesoid X receptor (FXR) antagonist with propensity for accumulation and responsiveness in ileum

Natural anticancer and antioxidant

Specific inhibitor of several viruses belonging to the family of flaviviridae

Novel Inhibitor of FKBP12

Novel non-peptide bradykinin (BK)-B2 receptor antagonist

Highly potent membrane-permeable ligand of the immunophilin FKBP12, creating a new composite FKBP12-FK506 surface and inactivating calcineurin, a Ca calmodulin-dependent protein phosphatase

Fluorescent protein-protein interaction (PPI) inhibitor

Natural potent cytotoxic agent

Antibacterial agent, expressing enhanced activity at acidic pH