Novel modulator of the PIN1 accumulation, selectively modifying PIN1 basal plasma membrane targeting in Arabidopsis with minimal effects on apical plasma membrane proteins

Specific inhibitor for plant callose deposition during cytokinesis without affectting endomembrane trafficking during interphase or cytoskeletal organization

Novel inhibitor of eukaryotic ARF-GEFs (ADP-ribosylation factor guanine nucleotide exchange factors)

Specific inhibitor of trafficking pathways, disrupting recycling at the PM via interference with ROP6/RIC1 signalling

Natural vesicle trafficking inhibitor

Antimalarial

Useful pharmceutical building block

Novel Potentiator of α7 Receptor Signaling

Novel butyrylcholinesterase inhibitor against Alzheimer's disease

Novel non-steroidal CYP17 inhibitor. reducing androgen synthesis for treatment of castration-resistant prostate cancer

Antioxidant, inhibiting free radical oxidation of biomembrane lipids, modulating the activity of membrane-bound enzymes and the receptor complexes of the brain membranes

Novel Potent and Selective Inhibitor of Protein Arginine Methyltransferase 4 (PRMT4)

Novel PRMT inhibitor, preventing arginine methylation of cellular proteins, being essentially inactive against the lysine methyltransferase SET7/9

5-FU derivative, with various anticancer agents against human cancer xenografts

Novel corticotropin-release factor 1 antagonist

Novel peptide endomorphin (EM) degradation blocker

Novel peptide endomorphin (EM) degradation blocker

Novel peptide endomorphin (EM) degradation blocker

Non-peptide angiotensin II receptor antagonist

PDE 3 inhibitor

Novel potent and highly selective c-Met inhibitor

Novel potent antitumor agent, inducing apoptosis in a panel of tumor cell lines

High affinity ligand for estrogen receptor-

Novel BCL-2 inhibitor, neutralizing the antiapoptotic activity of overexpressed BCL-2 toward staurosporine and sensitizing BCL-2-expressing cells from leukemic patients to the killing effects of staurosporine, chlorambucil, and fludarabine

Eukaryotic Ribosomal Selective Glycoside (ERSG), inducing read-through of premature stop codons (PSCs) and resulting in translation of full-length protein

Novel highly potent, selective, and CNS-penetrant inhibitor of elongation of very long chain fatty acid 1 (ELOVL1) enzyme

Novel γ-secretase inhibitor

Oleoylethanolamide-modelled PPAR

Novel ligand of the apelin receptor (APJ), possessing high affinity for APJ (Ki 4.6 nM) and producing cardiorenal effects in vivo similar to those of ELA

Novel inhibitor of Aurora B kinase