Foster Resonance Energy Transfer (FRET) pair for Aβ40 aggregates

Novel probe for selectively detecting sAβ species in Alzheimer's disease (AD)

Novel potent HDAC8 inhibitor

Novel NIR-II probe, noninvasively and dynamically visualizing and monitoring many physiological and pathological conditions of circulatory systems, including lymphatic drainage and routing, angiogenesis of tumor, and vascular deformity such as arterial th

Novel RORγt inhibitor, suppressing Th17 cell differentiation, reducing the severity of experimental autoimmune disease models such as EAU, EAE, and type 1 diabetes

Novel RORγt inhibitor, suppressing Th17 cell differentiation, reducing the severity of experimental autoimmune disease models such as EAU, EAE, and type 1 diabetes

Liposomal-encapsulated combination of daunorubicin and cytarabine for the treatment of newly diagnosed tAML or AML with myelodysplasia-related changes (AML-MRCs)

Novel potent and selective fluorescent inhibitor of glutaminase (GLS1)

Novel endothelin receptor antagonist, suppressing the upregulation of matrix metalloproteinases and connexin 43 in hyperthyroid myocardium

Novel inhibitor of death-associated protein kinase 1 (DAPK1), also inhibiting VEGF-receptor 2 and tyrosine-protein kinase SRC

Novel positive allosteric modulator (PAM) of metabotropic glutamate receptor 5 (mGlu5)

Novel selective NADPH oxidase 2 (Nox2) inhibitor, attenuating endothelial cell inflammation and vessel dysfunction and restoring mouse hind-limb flow

Novel selective NADPH oxidase 2 (Nox2) inhibitor, attenuating endothelial cell inflammation and vessel dysfunction and restoring mouse hind-limb flow

Novel CpIMPDH inhibitor

Unique inhibitor of MDM2, inhibiting MDM2-p53 interaction and promoting MDM2 degradation

Novel selective inhibitor of the CREB binding protein (CBP)

Novel potent inhibitor of CpFIKK catalytic activity

Novel non-RBD binding modulator to inhibit SARS-CoV-2 by prohibiting the conformational change of the spike (S) protein

Novel inhibitor of against human liver FBPase (IC50, 0.029±0.006 μM) and high selectivity relative to the other six AMP-binding enzymes, producing significant glucose-lowering effects on both type 2 diabetic KKAy mice and ZDF rats

Novel nonnucleoside reverse transcriptase inhibitor (NNRTI)

Potent PPARα agonist with a Ki of 10.8 nM

Novel Mdr1 P-glycoprotein substrate

Novel selective α5 GABA A receptor agonist

Inhibitor of Kv1.3 potassium ion channels

Inhibitor of glycogen phosphorylase; Antidiabetic

Novel potent and selective p38alpha inhibitor

Potent and selective leukotriene B4 antagonist

Novel viral propagation inhibitor, binding to the revised attenuator hairpin structure of the SARS-CoV-2 frameshifting element (FSE), stabilizing the hairpin's folded state and reducing frameshifting efficiency in cells

Novel Potent Mitochondria-Targeted Photodynamic Therapy Anticancer Agent

Novel Dual Covalent Inhibitor and Potential Fluorescent Label of HadA in Mycobacterium tuberculosis