Novel inhibitor of thioredoxin reductase (TrxR)

Antiatherosclerotic, antihyperlipidemic, antiinflammatory, antifungal, antiviral and antineoplastic

Inhibitor of the Cdc42-PBD interaction, blocking the association of Cdc42 with the PBD

Potent human sex hormone binding globulin (SHBG) ligand

Potent and selective JNK inhibitor; Analogue of SP600125 with improved potency and selectivity

Non-hydrolyzable ATP analog, acting as an effective and selective NTPDase2 inhibitor

Novel potent natural STAT3 signaling inhibitor from Polygonum cuspidatum, inhibiting cell growth and inducing apoptosis of HCC cells and HCC Cancer stem cells.

Endogenous superagonist of transient receptor potential melastatin 2 (TRPM2)

Inhibitor of cellular glycosylation; Analytical standard

Site BI- selective synergistic activator of PKA I

Lipid mediator, regulates neuronal apoptosis in traumatic brain injury (TBI)

Metabotropic Glutamate Receptor 5-selective Negative Allosteric Modulator

Novel potent activator of both human and mouse TLR4-NF-κB reporter cells and primary cells, inducing serum anti-HA and anti-NA IgG1 levels

Novel GPR88 Agonist

Novel selective inhibitor of EGFR kinase, leading to inactivation of PI3K/AKT/mTOR and Ras-Raf-MEK-ERK signal pathways

Novel Selective LXRβ Agonist

Oxysterol agonist of the liver X receptor

Novel Versatile Probe for Interrogating Histone Benzoylation and Interactions in Living Cells

Stimulator of the central nervous system, decreasing the 5-hydroxytryptamine (5-HT) and 5-hydroxyindoleacetic acid (5-HIAA) levels in brain

Concentration- and time-dependent inhibitor of the growth of NSCLC cells inducing apoptosis

Inhibitor of SykM442A S505A ASKA- (analog-sensitive kinase alleles) mediated cellular calcium flux

Natural Inhibitor for FcεRI expression on mast cell from Verbasucum thapsus L

Novel potent antiangiogenic agent, binding to VEGFR2, significantly reducing neovascularization in both ex vivo and in vivo angiogenic assays without affecting the proliferation of endothelial cells

Novel inhibitor of thioredoxin reductase (TrxR)

inactive isomeric impurity of Alphacalcidol

The first organic NO2-containing molecule isolated from plants, stimulating the soluble guanylate cyclase-cGMP pathway

Building Block

Building Block

Building Block

Reporter molecule functionalized at the anomeric position, exhibiting robust labeling over background with negligible amounts of nonspecific chemical labeling in cell lysates