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| Cat. No. | Product Name | Field of Application | Chemical Structure |
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| DC77868 | C2NP sodium |
C2NP sodium is a single-strand DNA aptamer that targets CD30. The multivalent C2NP is able to induce oligomerization of CD30 receptors and, in effect, activate downstream signaling, which led to apoptosis of anaplastic large cell lymphoma (ALCL) cells.
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| DC77867 | RLA-3107 |
RLA-3107 is an artemisinin regioisomer that blocks ion channels, thereby preventing cations from entering the host cytoplasm. RLA-3107 is also a viroporin inhibitor.
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| DC77866 | BMS-986497 |
BMS-986497 (ORM-6151) is a CD33-targeted antibody-conjugated GSPT1 degrader. BMS-986497 delivers the GSPT1 degrader SMol006 to CD33-expressing cells, inducing GSPT1 protein degradation. BMS-986497 is promising for research of acute myeloid leukemia (AML).
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| DC77865 | Belcesiran |
Belcesiran, a siRNA, is an alpha 1 antitrypsin (A1AT) inhibitor that acts by allowing the liver to synthesise the A1AT protein and pass it into the bloodstream.
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| DC77864 | Belcesiran sodium |
Belcesiran is an alpha 1 antitrypsin (A1AT) inhibitor that acts by allowing the liver to synthesise the A1AT protein and pass it into the bloodstream.
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| DC77863 | Beclanorsen |
Beclanorsen is an antisense oligonucleotide targeted to the mRNA of the Bcl-2 oncoprotein.
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| DC77862 | Beclanorsen sodium |
Beclanorsen sodium is an antisense oligonucleotide targeted to the mRNA of the Bcl-2 oncoprotein.
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| DC77861 | Bazlitoran |
Bazlitoran, an oligonucleotide, is an antagonist of TLR7, TLR8, and TLR9.
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| DC77860 | Bazlitoran sodium |
Bazlitoran sodium, an oligonucleotide, is an antagonist of TLR7, TLR8, and TLR9.
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| DC77859 | Archexin |
Archexin is an antisense oligonucleotide (ASO) against Akt1. It is used for the study of metastatic renal cancer.
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| DC77858 | Archexin sodium |
Archexin sodium is an antisense oligonucleotide (ASO) against Akt1. It is used for the study of metastatic renal cancer.
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| DC77857 | ARC5690 sodium |
ARC5690 sodium is an anti-mouse P-selectin aptamer. ARC5690 bound to recombinant mouse P-selectin with a KD of approximately 15pM in vitro. ARC5690 showed a significant anti-inflammatory effect
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| DC77856 | aptTNF-α sodium |
aptTNF-α sodium is a TNF-α-targeting aptamer that has tissue protective effect and systemic anti-inflammatory effect upon acute tissue injury using the mouse acute lung injury (ALI) and acute liver failure (ALF) models.
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| DC77855 | Apazunersen |
Apazunersen is an antisense oligonucleotide (ASO) that targets and inhibits expression of the UBE3A antisense transcript (UBE3A-AS) to prevent silencing of the paternally inherited allele of the UBE3A gene and reactivate expression of the deficient protei
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| DC77854 | Apazunersen sodium |
Apazunersen sodium is an antisense oligonucleotide (ASO) that targets and inhibits expression of the UBE3A antisense transcript (UBE3A-AS) to prevent silencing of the paternally inherited allele of the UBE3A gene and reactivate expression of the deficient
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| DC77853 | ALN-3133 sodium |
ALN-3133 sodium is a siRNA that targets VEGF, and it is one of the siRNAs in ALN-VSP.ALN-VSP is a lipid nanoparticle formulation containing two siRNAs for kinesin spindle protein (KSP) and VEGF with potential antitumor activity.
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| DC77852 | ALN-12115 |
ALN-12115 is a siRNA that targets kinesin spindle protein (KSP), and it is one of the siRNAs in ALN-VSP.ALN-VSP is a lipid nanoparticle formulation containing two siRNAs for KSP and VEGF with potential antitumor activity.
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| DC77851 | ALN-12115 sodium |
ALN-12115 sodium is a siRNA that targets kinesin spindle protein (KSP), and it is one of the siRNAs in ALN-VSP.ALN-VSP is a lipid nanoparticle formulation containing two siRNAs for KSP and VEGF with potential antitumor activity.
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| DC77850 | AGN-745 |
AGN-745 is a chemically modified siRNA targeted to VEGFR-1. It is used for the study of Macular degeneration.
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| DC77849 | AGN-745 sodium |
AGN-745 sodium is a chemically modified siRNA targeted to VEGFR-1. It is used for the study of Macular degeneration.
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| DC77848 | Agazisiran |
Agazisiran, a siRNA,is a complement factor B synthesis reducer.
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| DC77847 | Agazisiran sodium |
Agazisiran sodium, a siRNA,is a complement factor B synthesis reducer.
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| DC77846 | Afovirsen |
Afovirsen is a 20-mer phosphorothioate oligonucleotide. It is complementary to the mRNA sequence for the translation initiation codon of the E2 protein vital to replication of HPV types 6 and 11.
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| DC77845 | Afovirsen sodium |
Afovirsen sodium is a 20-mer phosphorothioate oligonucleotide. It is complementary to the mRNA sequence for the translation initiation codon of the E2 protein vital to replication of HPV types 6 and 11.
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| DC77844 | A9g sodium |
A9g sodium is an RNA aptamer that inhibits the enzymatic activity of prostate-specific membrane antigen (PSMA).
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| DC77843 | 148.1-38m sodium |
148.1-38m sodium, an RNA aptamer, inhibits HIV-1 reverse transcriptase (RT) and interfere with viral replication.
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| DC77842 | Calderasib (MK-1084) |
Calderasib (MK-1084) is a selective KRAS G12C inhibitor demonstrating antitumor efficacy. It can be utilized as monotherapy or in combination with pembrolizumab () for oncology research.
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| DC77841 | Cephalexin hydrochloride |
Cephalexin (hydrochloride, Cefalexin hydrochloride) is a potent, orally active cephalosporin antibiotic with broad-spectrum activity. It acts by binding to penicillin-binding proteins (PBPs), thereby disrupting bacterial cell wall synthesis. Cephalexin hydrochloride demonstrates antibacterial activity against a wide variety of gram-positive and gram-negative bacteria.
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| DC77840 | Emzadirib |
Emzadirib, an inhibitor of RAD51, exhibits a reduction in RAD51 foci. This compound displays significant anti-tumor activity with tumor growth inhibition in in vivo and in vitro models.
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| DC77839 | Ribociclib succinate hydrate |
Ribociclib succinate hydrate is an orally bioavailable and selective, inhibitor of both CDK4 and CDK6 with IC50 values of 10 nM and 39 nM, respectively. It exhibits anticancer activitiy and can be used in breast cancer, melanoma, liposarcoma, non–small cell lung cancer, and neuroblastoma therapy research.
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