Cas No.: | 13589-06-5 |
Synonyms: | BNC210,BNC-210,BNC 210 |
SMILES: | CC[C@H](C)[C@@H](C(=O)N[C@@H](CC1=CNC2=CC=CC=C21)C(=O)O)N |
Formula: | C17H23N3O3 |
M.Wt: | 317.38 |
Purity: | >98% |
Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Publication: | [1]. Toby Wise, et al. Cholinergic Modulation of Disorder-Relevant Neural Circuits in Generalised Anxiety Disorder (GAD) by BNC210, a negative allosteric modulator of α7 nAChR. |
Description: | BNC210 (H-Ile-Trp-OH; IW-2143) is a α7 nAChR negative allosteric modulator. BNC210 has potent activity in animal models of anxiety and depression[1]. |
References: | [1]. Toby Wise, et al. Cholinergic Modulation of Disorder-Relevant Neural Circuits in Generalised Anxiety Disorder (GAD) by BNC210, a negative allosteric modulator of α7 nAChR. |