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Pyrantel

  Cat. No.:  DC72214   Featured
Chemical Structure
15686-83-6
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More than 5000 active chemicals with high quality for research!
Field of application
Pyrantel is an orally active anthelmintic and an agonist of the nicotinic acetylcholine receptor (nAChR). Pyrantel can cause spasmodic muscle paralysis in parasites. Pyrantel can be used in the study of parasitic infections such as ascariasis, hookworm infections, intestinal worms (pinworm infections), trichinosis and trichinosis.
Cas No.: 15686-83-6
Chemical Name: 1-methyl-2-(E)-2-(thiophen-2-yl)ethenyl-1,4,5,6-tetrahydropyrimidine
Synonyms: pyrante;banminth;Pyrantel Base;PYRANTEL PARMOATE;PYRANTELUM;Pyrimidine, 1,4,5,6-tetrahydro-1-methyl-2-(1E)-2-(2-thienyl)ethenyl-;4,5,6-tetrahydro-1-methyl-2-(2-(2-thienyl)ethenyl)-(e)-pyrimidin;pyrequan;Pyrantel;1,4,5,6-Tetrahydro-1-methyl-2-[(E)-2-(2-thienyl)vinyl]pyrimidine;1-methyl-2-(2-thiophen-2-ylvinyl)-1,4,5,6-tetrahydro-pyrimidine;1-methyl-2-(trans-2-thiophen-2-yl-vinyl)-1,4,5,6-tetrahydro-pyrimidine;strongid;1-methyl-2-(E)-2-(thiophen-2-yl)ethenyl-1,4,5,6-tetrahydropyrimidine;Pirantel (INN-Spanish);Konvermex;E-1,4,5,6-Tetrahydro-1-methyl-2-(2-(2-thienyl)vinyl)pyrimidine;PYRANTEL [INN];DB11156;Pirantele;D08451;1-methyl-2-[(E)-2-thiophen-2-ylethenyl]-5,6-dihydro-4H-pyrimidine;HMS1541D15;HSDB 3252;CHEMBL1626223;HY-12641A;Pin-X;AB00053538_08;5686-02-2;(E)-1-Methyl-2-(2-(thiophen-2-yl)vinyl)-1,4,5,6-tetrahydropyrimidine;4QIH0N49E7;1-methyl-2-[(E)-2-(thiophen-2-yl)ethenyl]-1,4,5,6-tetrahydropyrimidine;Pyrantel [INN:BAN];SR-01000802778-4;1,4,5,6-tetrahydro-1-methyl-2-[(1e)-2-(2-thienyl)ethenyl]-pyrimidine;1-methyl-2-[(E)-2-(2-thienyl)vinyl]-5,6-dihydro-4H-pyrimidine;Pyrantelum (INN-Latin);1-methyl-2-((E)-2-(2-thienyl)vinyl)-1,4,5,6-tetrahydropyrimidine;pyrantel-pamoate;NCGC00174007-01;Q426897;MLS006011881;SCHEMBL164730;Pirantel;PYRANTEL [HSDB];1-methyl-2-(2-thiophen-2-ylethenyl)-5,6-dihydro-4H-pyrimidine;P02CC01;EINECS 239-774-1;PYRIMIDINE, 1,4,5,6-TETRAHYDRO-1-METHYL-2-(2-(2-THIENYL)ETHENYL)-;BRD-K20672254-046-02-1;1-Methyl-2-[(E)-2-(2-thienyl)ethenyl]-1,4,5,6-tetrahydropyrimidine #;SMR004703508;Pyrimidine, 1,4,5,6-tetrahydro-1-methyl-2-[2-(2-thienyl)ethenyl]-;AB00053538-07;Pyrimidine, 1,4,5,6-tetrahydro-1-methyl-2-(2-(2-thienyl)vinyl)-, (E)-;NCGC00174007-02;(Z)-1-Methyl-2-(2-(thiophen-2-yl)vinyl)-1,4,5,6-tetrahydropyrimidine;EN300-8684101;1-Methyl-2-(2-(thiophen-2-yl)vinyl)-1,4,5,6-tetrahydropyrimidine;UNII-4QIH0N49E7;E-1,4,5,6-TETRAHYDRO-1-METHYL-2-;NS00004940;SR-01000802778;Pyrantel (INN);Konvermex (TN);YSAUAVHXTIETRK-AATRIKPKSA-N;15686-83-6;BRD-K63072637-046-01-2;Pyrimidine, 1,4,5,6-tetrahydro-1-methyl-2-(2-(2-thienyl)ethenyl)-, (E)-;Pin-Rid;AKOS005594318;CS-0013762;A906579;Pirantel [INN-Spanish];PYRANTEL [VANDF];Pyrantelum [INN-Latin];PYRANTEL [MI];CHEBI:8654;PYRANTEL [WHO-DD];1-Methyl-2-[(E)-2-(2-thienyl)ethenyl]-1,4,5,6-tetrahydropyrimidine;C07409;DTXSID5023538;Pirantele [DCIT];1-methyl-2-[(E)-2-(2-thienyl)vinyl]-1,4,5,6-tetrahydropyrimidine;DTXCID403538;CHEBI:94685;BRD-K20672254-046-04-7;BRD-K20672254-096-03-4;STK676402;BRD-K20672254-096-05-9;BRD-K20672254-046-03-9;36700-38-6
SMILES: S1C=CC=C1/C=C/C1=NCCCN1C
Formula: C11H14N2S
M.Wt: 206.307260990143
Purity: 98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Cat. No. Product name Field of application
DC72214 Pyrantel Pyrantel is an orally active anthelmintic and an agonist of the nicotinic acetylcholine receptor (nAChR). Pyrantel can cause spasmodic muscle paralysis in parasites. Pyrantel can be used in the study of parasitic infections such as ascariasis, hookworm infections, intestinal worms (pinworm infections), trichinosis and trichinosis.
DC41803 α-Conotoxin MII α-Conotoxin MII is a highly potent and selective competitive antagonist for α3β2 subunit-containing nicotinic receptors (IC50 = 0.5 - 3.5 nM at α3β2 expressed in Xenopus oocytes). Also potently blocks β3-containing neuronal nicotinic receptors. Displays > 200-fold selectivity for α3β2 over α2β2, α4β2 and α3β4.
DC29057 Mecamylamine hydrochloride Mecamylamine hydrochloride is an orally active, nonselective, noncompetitive nAChR antagonist that can treat various neuropsychiatric disorders. Mecamylamine hydrochloride is originally used as a ganglionic blocker in treating hypertension. Mecamylamine hydrochloride can easily crosses the blood-brain barrier.
DC28701 nAChR agonist 1(DUN71755) nAChR agonist 1 is a potent, brain-permeable, and orally efficacious positive allosteric modulator of α7 nicotinic acetylcholine receptor (α7 nAChR). nAChR agonist 1 has the EC50 of 0.32 µM in a Ca2+ mobilization assay (PNU-282987-induced, FLIPR based) in human IMR-32 neuroblastoma cells that endogenously express α7 nAChR. nAChR agonist 1 can be develpoped for the treatment of Alzheimer’s disease.
DC28187 Asoxime dichloride Asoxime dichloride (HI-6) is an antagonist to acetylcholine receptors (AChRs) including the nicotinic receptor, α7 nAChR. Asoxime dichloride involves in modulating immunity response. Asoxime dichloride (HI-6) can be used as an antigen and improves vaccination efficacy in the nervous system.
DC28174 BNC210 BNC210 (H-Ile-Trp-OH; IW-2143) is a α7 nAChR negative allosteric modulator. BNC210 has potent activity in animal models of anxiety and depression.
DC11247 Nelonicline Nelonicline (ABT-126) is a potent, selective α7 nicotinic receptor (nAChR) partial agonist for the treatment of cognitive impairment with schizophrenia..
DC7987 Encenicline hydrochloride (EVP-6124) Encenicline hydrochloride (EVP-6124 hydrochloride) is a novel partial agonist of α7 neuronal nicotinic acetylcholine receptors (nAChRs).
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