Novel anti-influenza agent, interrupting the crucial RNP trafficking, resulting in influenza replication inhibition, preventing virus-induced cytopathic effects

Potent and selective antagonist of melanocortin-4 receptor (MC4R)

Novel PPK1 inhibitor, preventing UTI effectively through the disruption of the PPK1 function

Novel PPK1 inhibitor, preventing UTI effectively through the disruption of the PPK1 function

Novel pan-RAS-effector PPI inhibitor

Novel insulin mimetic

Novel inhibitor of protein-protein interaction (PPI), blocking #212121; font-family: BlinkMacSystemFont, -apple-system, "Segoe UI", Roboto, Oxygen, Ubuntu, Cantarell, "Fira Sans", "Droid Sans", "Helvetica Neue", sans-serif; font-size: 14px; font-style: no

Novel dual PPARα/γ agonist, ameliorating insulin resistance and gluconeogenesis in vivo and vitro

The first reported PPARα/δ dual antagonist

Novel iNOS homodimerization inhibitor

Novel pan-human EGF receptor (HER) inhibitor

Hypobetalipoproteinemic and Lipid decreasing agent

Potent Activator of Vγ9Vδ2 T-Lymphocytes; HMBPP ananlog prodrug

Novel pan-inhibitor of KCa3.1/KCa2 channels

Antibiotic as a last-line therapy to treat infections caused by these life-threatening 'superbugs'

Novel activator of Adenosine monophosphate (AMP)-activated protein kinase (AMPK)

Used for the transfection of a broad variety of cell lines; Antimicrobial; Novel binding agent of diffusive gradients in thin-films (DGT) technique (PEI-DGT)

Pan-Specific Inhibitor of the Polo-Box Domains of Polo-like Kinases Arrests Cancer Cells in Mitosis

Novel modulator of protein-protein interactions of the mitotic polo-like kinases, targeting KRAS mutant xenografts, indicate avenues, acting synergistically with Crizotinib, an inhibitor of the c-MET receptor, against mutant KRAS-expressing cancer cells

Novel macrocycle antibiotic with selective and potent activity against P. aeruginosa

Novel RNA polymerase I inhibitor, targeting ribosomal DNA G-quadruplexes, potently and selectively inhibiting cell growth by high-affinity binding to G4s in ribosomal DNA, impairing RNA polymerase I (Pol I) elongation, inducing a rapid inhibition of Pol I

Novel microtubule destabilizing natural product from the Podophyllum species

The first small-molecule approach capable of detecting and controlling engineered cell-cell outputs

Allosteric modulator of 5-HT(2C)R with no intrinsic agonist activity

Potent inhibitor of CDK2/cyclin A

Novel G Protein-Biased Cannabinoid 1 (CB1) Receptor Agonist

Cell-permeable analog of pifithrin-α, potently blocking p53-mediated expression of p21/WAF1 and apoptosis

Selective 5-HT1A serotonin receptor antagonist

Novel inhibitor of prenylated methylated protein methyl esterase (PMPMEase), a key enzyme in the reversible methylation/demethylation step in the protein prenylation pathway

Novel inhibitor of prenylated methylated protein methyl esterase (PMPMEase), a key enzyme in the reversible methylation/demethylation step in the protein prenylation pathway