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Inhibitors & Agonists

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Cat. No. Product Name Field of Application Chemical Structure
DC45406 Iso-Sagittatoside A
Iso-Sagittatoside A is the metabolite of effective Erxian Decoction (EXD, a Chinese medicine prescription for menopausal syndromes) in rat plasma.
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DC45405 Chamaechromone
Chamaechromone is a biflavonoid ingredient isolated from the roots of Stellera chamaejasme L. (Thymelaeaceae). Chamaechromone possesses anti-hepatitis B virus (HBV) effects against the surface antigen of HBV (HBsAg) secretion and has insecticidal activities.
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DC45404 Guvacoline hydrochloride
Guvacoline hydrochloride, a pyridine alkaloid found in Areca triandra, can act as a weak full agonist of atrial and ileal muscarinic receptors.
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DC45403 Isohemiphloin
Isohemiphloin is a flavonoid compound.
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DC45402 Pseudojervine
Pseudojervine is a glycoalkaloid with a feeble inhibition activity against platelet aggregation.
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DC45401 4-Feruloylquinic acid
4-Feruloylquinic acid may be a potential biomarker for food products.
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DC45400 Damulin B
Damulin B is a dammarane-type saponin found in Gynostemma pentaphyllum.Damulin B can induce cell apoptosis and has anti-cancer activities in vitro.
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DC45399 6'-O-β-Apiofuranosylsweroside
6'-O-β-Apiofuranosylsweroside is a secoiridoid glycoside that can be isolated from the leaves of Lonicera angustifolia Wall.
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DC45398 Lappaol A
Lappaol A is a natural compound with antiaging activity.
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DC45397 4aα,7α,7aα-Nepetalactone
4aα,7α,7aα-Nepetalactone exhibits antibacterial activity, and inhibits Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, Salmonella typhi and Enterococcus faecalis.
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DC45395 NSP-AS
NSP-AS is chemiluminescent acridinium substrate II and can be used in homo geneous assays.
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DC45394 Marmesinin
Marmesinin ((-)-Marmesinin), a natural coumarin, is a biosynthetic precursor of psoralen and linear furanocoumarins. Marmesinin exhibits significant neuroprotective activities against glutamate-induced toxicity.
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DC45393 4',4'''-Di-O-methylisochamaejasmin
4',4'''-Di-O-methylisochamaejasminexhibits anti-cancer effect.
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DC45392 Cycloartenyl ferulate
Cycloartenyl ferulate (Cycloartenol ferulate) is one of the typical triterpene alcohols and possesses several biological activities including anti-oxidative activity, antiallergic activity, anti-inflammatory and anticancer activities.
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DC45391 HKSOX-1m (5/6-mixture) (hydrobromide)
HKSOX-1m (5/6-mixture) hydrobromide is a O2•− fluorescent probe for mitochondria-targeting, exhibiting excellent selectivity and sensitivity toward O2•− over a broad range of pH, strong oxidants, and abundant reductants found in cells.
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DC45390 3'-Deoxyuridine-5'-triphosphate trisodium
3'-Deoxyuridine-5'-triphosphate trisodium (3'-dUTP trisodium) is a nucleotide analogue that inhibits DNA-dependent RNA polymerases I and II. 3'-Deoxyuridine-5'-triphosphate trisodium strongly and competitively inhibits the incorporations of UTP into RNA with a Ki value of 2.0 μM.
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DC45389 Glycerophosphoric acid disodium salt hydrate (α and β mixture)
Glycerophosphoric acid (disodium salt hydrate) (α and β mixture) is a complex contains α and β Glycerophosphoric acid isomers.
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DC45388 Pomiferin
Pomiferin (NSC 5113) acts as an potential inhibitor of HDAC, with an IC50 of 1.05 μM, and also potently inhibits mTOR (IC50, 6.2 µM).
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DC45387 EMD527040
EMD527040 is a potent and highly selective αvβ6 antagonist with antifibrotic activities. EMD527040 can be used for carcinoma and liver fibrosis research.
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DC45386 Combretastatin A-1
Combretastatin A-1 is a microtubule polymerization inhibitor that binds to the colchicine-binding site of tubulin. Combretastatin A-1 inhibits the Wnt/β-catenin pathway through tubulin depolymerization mediated AKT deactivation. Combretastatin A-1 exhibits anti-tumor and anti-vascular effects.
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DC45385 CP-346086 dihydrate
CP-346086 dihydrate is a potent and orally active microsomal triglyceride transfer protein (MTP) inhibitor, with an IC50 of 2.0 nM for human and rodent MTP. CP-346086 dihydrate can lower plasma cholesterol and triglycerides in vivo.
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DC45384 LUF6096
LUF6096, a potent allosteric enhancer of the adenosine A3 receptor, is able to allosterically enhance agonist binding. LUF6096 shows low orthosteric affinity for any of the adenosine receptors. LUF6096 shows protective effects in myocardial ischemia/reperfusion injury.
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DC45383 Trimethobenzamide
Trimethobenzamide (Ro 2-9578 free base) is a blocker of the D2 receptor. Trimethobenzamide is an antiemetic used to prevent nausea and vomiting.
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DC45382 KW-8232
KW-8232, an orally active anti-osteoporotic agent, and can reduces the biosynthesis of PGE2.
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DC45380 Protein deglycase DJ-1 against-1
Protein deglycase DJ-1 against-1, a DJ-1-binding compound, dependently targets DJ1. Protein deglycase DJ-1 against-1 penetrates through the blood brain barrier (BBB). Protein deglycase DJ-1 against-1 is used as a neuroprotective agent and has the potential for Parkinson's disease research.
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DC45379 Tibolone
Tibolone is a broad spectrum gonadal steroid agonist with progestagenic, androgenic, and estrogenic activities. Tibolone can be used for postmenopausal osteoporosis research.
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DC45378 GPR30 agonist-1
GPR30 agonist-1 is a G protein-coupled receptor 30 (GPR30) agonist. GPR30 agonist-1 exerts vasorelaxant effects.
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DC45376 (Z)-Lafutidine
(Z)-Lafutidine ((Z)-FRG-8813) is a potent histamine H2 receptor antagonist. (Z)-Lafutidine shows anti-secretory and gastroprotective activities.
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DC45375 Tryptamine guanosine carbamate
Tryptamine guanosine carbamate (TpGc) is a selective HINT1 (histidine triad nucleotide-binding protein 1) inhibitor (Ki=34 μM, Kd=3.65 μM). Tryptamine guanosine carbamate significantly enhances morphine antinociception while preventing the development of tolerance.
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DC45374 Bruceoside A
Bruceoside A, an abundant quassinoid glycoside in Fructus Bruceae, possesses anti-cancer activity.
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