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Inhibitors & Agonists

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Cat. No. Product Name Field of Application Chemical Structure
DC45371 5-Benzyloxygramine
5-Benzyloxygramine is a N protein PPI orthosteric stabilizer that exhibits both antiviral and N-NTD protein-stabilizing activities.
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DC45370 UK122
UK122 is a potent and selective urokinase-type plasminogen activator (uPA) inhibitor with an IC50 of 0.2 μM. UK122 shows no or little inhibition of tissue-type PA (tPA), plasmin, thrombin, and trypsin (all IC50>100 μM). UK122, 4-oxazolidinone analogue, is an anticancer agent and inhibits cancer cell migration and invasion.
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DC45369 Octaethylene glycol monododecyl ether
Octaethylene glycol monododecyl ether (C12E8) is an non-ionic detergent that can be used for membrane protein extraction. Octaethylene glycol monododecyl ether can solubilize the viral membrane of intact influenza virus.
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DC45368 LCAHA
LCAHA (LCA hydroxyamide) is a deubiquitinase USP2a inhibitor with IC50s of 9.7 μM and 3.7μM in Ub-AMC Assay and Di-Ub Assay, respectively. LCAHA destabilizes Cyclin D1 and induces G0/G1 arrest by inhibiting deubiquitinase USP2a.
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DC45367 Latrunculin B
Latrunculin B, an antimicrobial marine alkaloid, is an actin polymerization inhibitor. Latrunculin B regulates pulmonary vein electrophysiological characteristics and attenuates stretch-induced arrhythmogenesis. Antifungal and antiprotozoal activity.
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DC45366 Bruceine B
Bruceine B inhibits protein synthesis and nucleic acid synthesis.
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DC45365 Boeravinone B
Boeravinone B, a dual inhibitor of NorA bacterial efflux pump of Staphylococcus aureus and human P-Glycoprotein, reduces the biofilm formation and intracellular invasion of bacteria. Boeravinone B act as anti-aging and anti-apoptosis phyto-molecules during oxidative stress.
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DC45364 Araloside C
Araloside C exhibits protective effects against myocardial ischaemia/reperfusion injury.
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DC45363 Andrograpanin
Andrograpanin, a bioactive compound from Andrographis paniculata, exhibits anti-inflammatory and anti-infectious properties.
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DC45362 Acetoxyvalerenic acid
Acetoxyvalerenic acid is a natural compound that could be found in valerian.
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DC45361 6-Benzoylheteratisine
6-Benzoylheteratisine is a naturally occurring antagonist of the Na+ channel activator aconitine.
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DC45360 17α-Hydroxyprogesterone acetate
17α-Hydroxyprogesterone acetate possesses progestational activity. 17α-Hydroxyprogesterone acetate has antiinflammatory effects at the murine maternal-fetal interface.
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DC45359 12S-HHT
12S-HHT (12(S)-HHTrE) is an enzymatic product of prostaglandin H2 (PGH2) derived from cyclooxygenase (COX)-mediated arachidonic acid metabolism. 12S-HHT is an endogenous ligand for BLT2 that fully activates BLT2 in vivo. 12S-HHT suppresses UV-induced IL-6 synthesis in keratinocytes, exerting an anti-inflammatory activity.
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DC45358 ER-Tracker Green
ER-Tracker Green is a fluorescent dye that specific for endoplasmic reticulum.
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DC45357 1,4-Dihydroxy-2-carbomethoxy-3-prenylnaphthalene-1-O-β-D-glucopyranoside
1,4-Dihydroxy-2-carbomethoxy-3-prenylnaphthalene-1-O-β-D-glucopyranoside is a dihydronaphtoquinone.
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DC45356 (2S)-7,4'-Dihydroxy-3'-prenylflavan
(2S)-7,4'-Dihydroxy-3'-prenylflavan is a natural product.
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DC45355 1α-Hydroxy-3-epi-vitamin D3
1α-Hydroxy-3-epi-vitamin D3, a natural metabolite of 1alpha,25-dihydroxyvitamin D3, is a potent suppressor of parathyroid hormone (PTH) secretion.
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DC45354 2-Methyl-1,3,6-trihydroxy-9,10-anthraquinone-3-O-α-rhamnosyl-(1→2)-β-D-glucoside
2-Methyl-1,3,6-trihydroxy-9,10-anthraquinone-3-O-α-rhamnosyl-(1→2)-β-D-glucoside is a natural product that can be isolated from the roots of Rubia cordifolia.
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DC45353 5-O-Caffeoylshikimic acid
5-O-Caffeoylshikimic acid can be used in the study for NSCLC.
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DC45352 6-Hydroxykaempferol 3-O-β-D-glucoside
6-Hydroxykaempferol 3-O-β-D-glucoside possesses anticancer activity and induces apoptosis.
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DC45351 Cnidicin
Cnidicin, a coumarin, inhibits the degranulation of mast cell and the nitric oxide (NO) generation in RAW 264.7 cells.
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DC45350 Decyl maltose neopentyl glycol
Decyl maltose neopentyl glycol (DMNG) is the neopentyl glycol detergent that does not disrupt the AlkB oligomeric state. AlkB is a nonheme di-iron alkane hydroxylase.
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DC45349 Fimaporfin
Fimaporfin (TPCS2a) is an endosomal/lysosomal-localizing photosensitizer.
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DC45348 NY2267
NY2267 is a disruptor of Myc-Max interaction, with an IC50 of 36.5 μM.
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DC45347 (R)-(4′-Hydroxy)-5,7-dihydroxy-4-chromanone
(R)-(4′-Hydroxy)-5,7-dihydroxy-4-chromanone, a homoisoflavonoid, has antiangiogenic activity against human retinal microvascular endothelial cells.
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DC45346 (1S)-Calcitriol
(1S)-Calcitriol (1α,25-Dihydroxy-3-epi-vitamin-D3) is a natural metabolite of 1α,25-dihydroxyvitamin D3 (1α,25(OH)2D3). (1S)-Calcitriol exhibits potent vitamin D receptor (VDR)-mediated actions such as inhibition of keratinocyte growth or suppression of parathyroid hormone secretion.
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DC45345 Futoquinol
Futoquinol is a neolignan isolated from the dried aerial parts of Piper kadsura (Piperaceae). Futoquinol potently inhibits NO production in microglia cells. Futoquinol has anti-neuroinflammatory activities.
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DC45344 Multicaulisin
Multicaulisin, a new Diels-Alder type adduct from Morus multicaulis roots, potently effects against Staphylococcus aureus (MRSA) isolates. Multicaulisin is an antibacterial drug and has the potential for MRSA infections research.
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DC45343 1αH,5αH-Guaia-6-ene-4β,10β-diol
1αH,5αH-Guaia-6-ene-4β,10β-diol is a sesquiterpenoid derivative identified from Alisma orientale. 1αH,5αH-Guaia-6-ene-4β,10β-diol has anti-cancer activities.
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DC45342 Catalposide
Catalposide, an iridoid glycoside that could be isolated from Catalpa ovate G. Don (Bignoniaceae), inhibits TNF-α, IL-1β, and IL-6 productions and NF-κB (p65) activation in lipopolysaccharide-activated RAW 264.7 macrophages.
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