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Novel inhibitors

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Cat. No. Product Name Field of Application Chemical Structure
DC45447 (+)-Epipinoresinol
(+)-Epipinoresinol is a lignan compound. CYP81Q3 specifically catalyzes methylenedioxy bridge (MDB) formation in (+)-Epipinoresinol to produce (+)-Pluviatilol.
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DC45446 11-Oxomogroside IIIE
11-Oxomogroside IIIE is a cucurbitane triterpene glycoside isolated from Lo Han Kuo (Siraitia grosvenori).
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DC45445 Fluticasone dimer impurity
Fluticasone dimer impurity is a dimeric impurity of Fluticasone Propionate. Fluticasone propionate is a corticosteroid with comparatively high receptor affinity and topical activity.
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DC45444 (-)-N-methylcoclaurine
(-)-N-methylcoclaurine possesses melanogenesis inhibitory activity.
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DC45443 Epimagnolin A
Epimagnolin A, a furfuran lignan, shows mild antiplasmodial activities (IC50=5.7 μg/mL) without noticeable toxicity on mammalian normal cells.
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DC45442 3-O-Acetyl-α-boswellic acid
3-O-Acetyl-α-boswellic acid suppresses T cell function.
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DC45441 2-(2-Phenylethyl)chromone
2-(2-Phenylethyl)chromone (Flidersiachromone) is one of 2-(2-phenylethyl)chromones that can be found in Chinese eaglewood from Aquilaria sinensis.
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DC45440 3'-Methoxyapiin
3'-Methoxyapiin (Graveobioside B) is a flavone. 3'-Methoxyapiin can be found in Uraria crinite and celery.
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DC45439 3'-Deoxy-4-O-methylsappanol
3'-Deoxy-4-O-methylsappanol shows cytotoxicity against melanoma HMV II cell (IC50=50.4 μM) and has significant anti-melanogenic activities (EC50=72 μM).
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DC45438 3-Hydroxymorindone
3-Hydroxymorindone is an anthraquinone and a pigment.
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DC45437 3-Hydroxy-4',5-dimethoxystilbene
3-Hydroxy-4',5-dimethoxystilbene is a natural compound found in stem bark of Morus nigra L.
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DC45436 2,4,7-Trihydroxy-9,10-dihydrophenanthrene
2,4,7-Trihydroxy-9,10-dihydrophenanthrene is a dihydrophenanthrene derivative that can be isolated from the air-dried whole plant of Pholidota chinensis Lindl.. 2,4,7-Trihydroxy-9,10-dihydrophenanthrene shows potent activities of IC50 at 16.2 μM in DPPH radical-scavenging assay.
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DC45435 3′,4′,5′,5,6,7-Hexamethoxyflavone
3′,4′,5′,5,6,7-Hexamethoxyflavone is a flavonoid with antiprotozoal activity. 3′,4′,5′,5,6,7-Hexamethoxyflavone inhibits trypanosoma bruceirhodesiense with IC50 of 21.3 μM (8.58 g/mL).
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DC45434 11-Oxomogroside IV
11-Oxomogroside IV is a natural compound that could be found in the fruits of Siraitia grosvenori.
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DC45433 2,4,6-Trichlorol-3-methyl-5-methoxy-phenol 1-O-β-d-glucopyranosyl-(1 → 6)-β-d-glucopyranoside
2,4,6-Trichlorol-3-methyl-5-methoxy-phenol 1-O-β-d-glucopyranosyl-(1 → 6)-β-d-glucopyranoside is a chlorophenyl glycoside found in the bulbs of Lilium brownie var. viridulum. 2,4,6-Trichlorol-3-methyl-5-methoxy-phenol 1-O-β-d-glucopyranosyl-(1 → 6)-β-d-glucopyranoside exhibits weak inhibition of NO production in LPS-stimulated RAW 264.7 cells.
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DC45432 3'-O-Methylbatatasin III
3'-O-Methylbatatasin III shows spasmolytic activity.
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DC45431 3-Oxobetulin
3-Oxobetulin, an antifungal agent, shows antifungal activities against white rot fungus L. betulina and the brown rot fungus L. sulphureus.
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DC45430 L-2-Aminooxy-3-phenylpropanoic acid
L-2-Aminooxy-3-phenylpropanoic acid is a potent inhibitor of L-phenylalanine ammonia-lyase.
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DC45429 3-O-Acetyl-16α-hydroxydehydrotrametenolic acid
3-O-Acetyl-16α-hydroxydehydrotrametenolic acid, an anti-inflammatory triterpenoid, inhibits NO production and iNOS expression in LPS-stimulated Raw264.7 cells.
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DC45428 3-Epidehydropachymic acid
3-Epidehydropachymic acid, a lanostane triterpenoid, shows totoxicity effect against human acute monocytic leukemia cell line THP-1 (IC50=52.51 μM).
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DC45427 3-Feruloylquinic acid
3-Feruloylquinic acid, a derivative of quinic acid-bound phenolic acid, shows antioxidant activity. 3-Feruloylquinic acid markedly enhances by high photosynthetically active radiation (PAR) and UV irradiances.
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DC45426 12-Deoxywithastramonolide
12-Deoxywithastramonolide is a principle bioactive compound found in ashwagandha (W. somnifera). 12-Deoxywithastramonolide possesses antioxidant and enzyme inhibitory effects.
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DC45425 5-O-Cinnamoylquinic acid
5-O-Cinnamoylquinic acid is a co-pigment. 5-O-Cinnamoylquinic acid could form the stable blue solution.
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DC45424 17,17-(Ethylenedioxy)androst-4-en-3-one
17,17-(Ethylenedioxy)androst-4-en-3-one (4-​androstene-​3,​17-​dione-​17-​cyclic ethylene ketal) is an effective ingredient in cosmetics, which can be used for acne and promote hair growth research. 17,17-(Ethylenedioxy)androst-4-en-3-one can inhibit the reductase activity and inhibit the bond of a receptor protein and 5α-DHT.
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DC45423 3β,7β,15β-Trihydroxy-11-oxo-lanosta-8-en-24→20 lactone
3β,7β,15β-Trihydroxy-11-oxo-lanosta-8-en-24→20 lactone is a natural compound that could be isolated from G. lucidum with antimycobacterial activity.
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DC45422 Cheilanthifoline
Cheilanthifoline, an alkaloid, is isolated from Corydalis calliantha. Cheilanthifoline exhibits antiplasmodial activities against Plasmodium falciparum, with IC50s of 0.90 μg/mL and 1.22 μg/mL for wild type (TM4) and multidrug resistant (K1) strains, respectively.
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DC45421 Protopseudohypericin
Protopseudohypericin, a naturally occurring naphthodianthrone, is isolated from H. perforatum. Protopseudohypericin is considered to be the biosynthetic precursor of Pseudohypericin.
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DC45420 4β,12-Dihydroxyguaian-6,10-diene
4β,12-Dihydroxyguaian-6,10-diene, a natural terpene, is isolated from the rhizomes of Alisma orientale.
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DC45419 (+)-Balanophonin
(+)-Balanophonin is a phenolic compound that could be isolated from Passiflora edulis. (+)-Balanophonin possesses anti-oxidant, anticholinesterase, anti-inflammatory, anticancer, and antineurodegenerative activities.
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DC45417 Eudesmol
Eudesmol is a sesquiterpenoid compound produced by Streptomyces tendae.
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