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Cat. No. Product Name Field of Application Chemical Structure
DC46330 pNP-ADPr
pNP-ADPr is a colorimetric substrate that used for the first continuous Poly(ADP-ribose) glycohydrolase (PARG) and ADP-ribosyl hydrolase 3 (ARH3) activity assays. pNP-ADPr can be used for the research of poly(ADP-ribose)polymerase (PARP) enzymes.
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DC46329 Phoyunnanin E
Phoyunnanin E, isolated from Dendrobium venustum, possesses anti-migration activity. Phoyunnanin E can be used for the research of cancer.
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DC46328 NHS-MMAF
NHS-MMAF is a modified MMAF extracted from patent WO2012143499, intermediat 219. MMAF is a potent tubulin polymerization inhibitor and is used as a antitumor agent
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DC46327 Methyl 5-hydroxypyridine-2-carboxylate
Methyl 5-hydroxypyridine-2-carboxylate is a phenolic acid that can found in the stems of Mahonia fortune. Methyl 5-hydroxypyridine-2-carboxylate exhibits NO inhibitory effects in vitro.
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DC46326 (±)-H3RESCA-TFP
(±)-H3RESCA-TFP ((±)-H3L28) is a tetrafluorophenyl ester derivative of restrained complexing agent (RESCA). (±)-H3RESCA-TFP can be used to conjugate the chelator with a biomolecule via amine coupling (e.g., N terminus and/or the ε-amino groups of lysine).
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DC46321 SiR-COOH
SiR-COOH could be used to follow the intracellular location of the model therapeutic drug in GFP cells (Abs, 645 nm; Em, 676 nm).
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DC46320 HBC599
HBC599 is a HBC analog. HBC is nonfluorescent in solution, but emits strong fluorescence upon forming tight complex with Pepper RNA aptamer. HBC-Pepper complex can be used to visualize RNA dynamics in live cells.
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DC46316 1-Methyl-2-[(Z)-6-undecenyl]-4(1H)-quinolone
1-Methyl-2-[(Z)-6-undecenyl]-4(1H)-quinolone, as a colorless oil, is a quinolone alkaloid isolated from the fruit of Evodia rutaecarpa BENTHAM (Rutaceae).
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DC46315 trans,trans-2,4-Decadienal
trans,trans-2,4-Decadienal is a lipid peroxidation product of linolieic acid.
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DC46313 Photo-lysine hydrochloride
Photo-lysine hydrochloride, a new lysine-based photo-reactive amino acid, captures proteins that bind lysine post-translational modifications.
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DC46312 Adipokinetic Hormone (AKH) (24-32), locust TFA
Adipokinetic Hormone (AKH) (24-32), locust (TFA), isolated from locust corpora cardiaca, is a neurohormone that regulates lipid utilisation during flight.
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DC46306 Ganciclovir mono-O-acetate
Ganciclovir mono-O-acetate is a derivative of Ganciclovir. Ganciclovir, a nucleoside analogue, is an orally active antiviral agent with activity against CMV.
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DC46305 4-Hydroxymephenytoin D3
4-Hydroxymephenytoin D3 is the deuterium labeled 4-Hydroxymephenytoin. 4-Hydroxymephenytoin is a metabolism of an antiepileptic drug mephenytoin, which is used as a CYP2C19 substrate.
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DC46304 Trimethylolpropane ethoxylate triacrylate
Trimethylolpropane ethoxylate triacrylate (ETPTA) is a plasticizer that can be used synthesize nanocomposites.
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DC46303 PFB-FDGlu
PFB-FDGlu is a selective lysosomal Glucocerebrosidase (GCase) substrate, which is metabolised by GCase to yield fluorescein. PFB-FDGlu is cell permeable and can be used with a flow cytometer to measure GCase activity in living cells on a single-cell basis.
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DC46302 Hexidium iodide
Hexidium iodide, a fluorescent nucleic binding acid stain (excitation/emission ~ 518/600 nm), permeants to mammalian cells and selectively stains almost all gram-positive bacteria. Hexidium iodide can bind to the DNA of all bacteria after permeabilization by EDTA.
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DC46284 L-Leucine-7-amido-4-methylcoumarin hydrochloride
L-Leucine-7-amido-4-methylcoumarin (Leu-AMC) hydrochloride is a bright blue fluorogenic peptidyl substrate for LAP3 (leucine aminopeptidase). L-Leucine-7-amido-4-methylcoumarin hydrochloride can be used for leucine aminopeptidase inhibition assays in vitro.
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DC46272 MAIT-203
MAIT-203, a cyclopentyalanin-derived peptidomimetic, potently inhibits the interaction of adenomatous polyposis coli (APC) and Asef (RhoGEF4), but not APC-Sam68 or APC-striatin interactions. MAIT-203 binds APC-ARM with a Ki of 0.015 μM and a Kd of 0.036 μM. MAIT-203 significantly represses the migration and invasion of colorectal cancer cells.
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DC46270 WRW4 TFA
WRW4 TFA, a specific formyl peptide receptor-like 1 (FPRL1) antagonist, inhibits WKYMVm binding to FPRL1 with an IC50 of 0.23 μM. WRW4 TFA specifically inhibits the increase in intracellular calcium by the FPRL1 agonists MMK-1, amyloid beta42 (Abeta42) peptide, and F peptide.
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DC46246 Ilexoside XLVIII
Ilexoside XLVIII is an acyl CoA cholesteryl acyl transferase (ACAT) inhibitor. Ilexoside XLVIII is a triterpene saponin isolated from an aqueous extract of the leaves of Ilex kudincha.
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DC46236 4-Methylumbelliferyl β-D-Glucopyranoside
4-Methylumbelliferyl β-D-Glucopyranoside, a β-D-glucoside, is a fluorogenic substrate for β-glucosidase, utilizes to assay β-glucosidase activity. 4-Methylumbelliferyl β-D-Glucopyranoside releases the highly fluorescent 4-methylumbelliferyl (4-MU), which has an emission maximum at 445-454 nm. The excitation maximum for 4-MU is pH-dependent: 330, 370, and 385 nm at pH 4.6, 7.4, and 10.4, respectively.
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DC46221 AZ-PFKFB3-67 quarterhydrate
AZ-PFKFB3-67 quarterhydrate is potent and selective metabolic kinase PFKFB3 inhibitor, with IC50s of 11, 159 and 1130 nM for PFKFB3, PFKFB2 and PFKFB1 respectively.
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DC46197 PbS/CdS QDs
PbS/CdS QDs (PbS/CdSe QD) is a fluorescent probe that can be used for in vivo fluorescence imaging in the second near-infrared window.
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DC46196 AgAuSe QDs
AgAuSe QDs (AgAuSe) is a near infrared (NIR) fluorescent quantum dots (QDs), with a bright emission from 820 to 1170 nm. AgAuSe QDs can be used for the research in biomedical imaging and NIR devices.
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DC46194 Abz-FRLKGGAPIKGV-EDDNP TFA
Abz-FRLKGGAPIKGV-EDDNP TFA is a fluorogenic substrate used to measure the enzymatic activities of protease forms, such as papain-like protease 2 (PLP2) from severe acute respiratory syndrome coronavirus (SARS-CoV). Abz-FRLKGGAPIKGV-EDDNP TFA has the potential for study 2019-nCoV (COVID-19) infection.
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DC42561 IMM-H007 Featured
Novel lipid-lowering agent, acting as an AMPK activator, increasing ABCA1 protein expression and improving hepatic lipid metabolism and leukocyte trafficking in experimental hepatic steatosis
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DC43184 DD1 Featured
Novel proteasome inhibitor, inducing human myeloid tumor-selective apoptosis
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DC46191 Compound W
Compound W (3,5-Bis(4-nitrophenoxy)benzoic acid) is an inhibitor of γ-secretase. Compound W causes a decrease in the released levels of Aβ42 and notch-1 Aβ-like peptide 25 (Nβ25).
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DC46188 NSC622608
NSC622608 is a first small-molecule ligand for V-domain Ig Suppressor of T-cell Activation (VISTA) with an IC50 of 4.8 μM in TR-FRET assay.
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DC46187 Triheptanoin
Triheptanoin (API, IND106011, UX007, Glycerol trienanthate) is a synthetic, medium-chain triglyceride consisting of three odd-chain 7-carbon (heptanoate) fatty acids on a glycerol backbone. Triheptanoin is used for treatment of fatty acid oxidation disorders and GLUT1.
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