Natural specific inhibitor of γ-secretase, decreasing amyloid-beta levels without influencing cleavage of Notch, showing strong growth inhibitory effects on cancer cell lines and significant anti-complement activity, also acting as a PTP1B inhibitor

Natural resveratrol trimer, acting as a protein kinase C inhibitor

Novel KGA allosteric inhibitor

Novel HuR binder, modulating HuR-RNA interactions

Potent and selective NMDA agonist

Metabolite of Resveratrol

Potent I 2 -imidazoline receptor agonist

Novel Type-I Inhibitor of TIE-2

Mitochondria-activatable luciferin (MAL-Probe)

Enhancer of the cytotoxic effect of immunotoxins (ITs) which results in increased apoptosis in different cancer cells

Novel tumour progression locus 2 (Tpl2) kinase inhibitor

Novel taxane family member, reducing the brain metastatic colonization of breast cancer cells

Novel Specific Inhibitor of Type I Collagen Production in Fibrosis

Promising amyloid reducing agent by lowering the levels of Aβ.

Inhibitor of tyrosine recombinases and Holliday junction-resolving enzymes; Antibacterial

Novel Peripheral Selective Tryptophan Hydroxylase 1 (TPH1) Inhibitor (IC 50 : 42nM) for Obesity and Fatty Liver Disease

First-in-class fluorescent drug delivery vesicle that can efficiently load both water-soluble and -insoluble anticancer drugs

Novel probe for CECR2/BPTF bromodomains

Novel inhibitor of O-GlcNAcase (OGA)

Novel probe for activin receptor-like kinase (ALK4 and ALK5)

Novel ToxT inhibitor, reducing Vibrio cholerae virulence in vivo and effectively inhibiting intestinal colonization in the infant mouse

Selective CA IX inhibitor

Chromogenic peptide substrate for the rapid and specific photometric assay of recombinant hirudin (r-hirudin)

Natural psychoactive agent

Nucleic acid stain, acting on viable, early apoptotic and necrotic cells differentially, showing specific staining of nuclei without any staining of the cytoplasm

Novel highly specific fluorescent TOPK inhibitor

Novel Selective Inhibitor of Endoplasmic Reticulum α-Glucosidase II, Exhibiting Antiflaviviral Activity

Novel narrow spectrum kinase inhibitor, potently inhibiting P38a, Src, and Syk kinase activities

Novel dual TOP1 and TDP1 inhibitor, inducing both cellular TOP1cc, TDP1cc formation and DNA damage, resulting in cancer cell apoptosis at a sub-micromolar concentration

Natural agonist of TPRC1/4/5 channels, also acting as a dual PKCα and PKCθ activator, inducing an insulin resistant phenotype by inhibiting IRS1 and the PI3K/Akt pathway, activating the heat shock factor 1 (HSF1) transcription factor driving glucose depen