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Cat. No. Product Name Field of Application Chemical Structure
DC72493 (R)-Elsubrutinib
(R)-Elsubrutinib ((R)-ABBV-105) is a Btk inhibitor. (R)-Elsubrutinib can be used in studies of immune diseases (such as rheumatoid arthritis, psoriasis, ankylosing spondylitis, asthma, systemic lupus erythematosus) and cancer.
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DC72491 ZG1077
ZG1077 is a covalent KRAS G12C inhibitor. ZG1077 can be used in the research of non-small cell lung cancer (NSCLC).
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DC72490 ASN007
ASN007(ERAS 007, ERK-IN-3) is a potent and orally active inhibitor of ERK. ERK-IN-3 inhibits ERK1/2 with 2 nM IC50 values. ERK-IN-3 can be used for the research of cancers driven by RAS mutations.
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DC72489 Ph-HTBA
Ph-HTBA is a high-affinity, brain-penetrating modulator for CaMKIIα. Ph-HTBA has binding affinity for CaMKIIα with a Kd value of 757 nM. Ph-HTBA can be used for the research of ischemia and neurodegenerative disorders.
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DC72488 Mangafodipir Trisodium
Mangafodipir trisodium (MnDPDP), hepatocellular-specific contrast agent, is an efficacious inhibitor of CIPN (chemotherapy-induced peripheral neuropath) and other conditions caused by cellular oxidative stress. Mangafodipir trisodium shows no negative interference with the tumoricidal activity of chemotherapy.
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DC72486 KPLH1130
KPLH1130 is a specific inhibitor of pyruvate dehydrogenase kinase (PDK) that blocks macrophage polarization and attenuates proinflammatory responses.
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DC72484 CTX-0294885
CTX-0294885, a bisanilino pyrimidine, is a novel broad-spectrum kinase inhibitor. CTX-0294885 is further developed into a Sepharose-supported kinase capture reagent.
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DC72482 (S,R,S)-AHPC hydrochloride
(S,R,S)-AHPC hydrochloride (VH032-NH2, VHL ligand 1) is the VH032-based VHL ligand that is applicable to the recruitment of the von Hippel-Lindau (VHL) protein. (S,R,S)-AHPC hydrochloride can be connected to the ligand for protein by a linker to form PROTACs.
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DC72481 NIR-βgal-2
NIR-βgal-2 is a β-galactosidase-activated near-infrared fluorescent probe with superior sensitivity. NIR-βgal-2 can be used for visualizing β-galactosidase in breast cancer.
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DC72480 UHMCP1 dihydrochloride
UHMCP1 dihydrochloride is a potent UHM domain splicing inhibitor with a Kd value of 79 µM. UHMCP1 dihydrochloride prevents the SF3b155/U2AF65 interaction. UHMCP1 dihydrochloride impacts cell viability and RNA splicing.
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DC72479 Hyocholic Acid
Hyocholic Acid is a bile acid found in pig. Hyocholic Acid can also be found in urine samples from patients with cholestasis. Hyocholic Acid promotes GLP-1 secretion via activating TGR5 and inhibiting FXR in enteroendocrine cells. Hyocholic Acid is known for its exceptional resistance to type 2 diabetes .
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DC72478 Phaseic acid
Phaseic acid is a Abscisic acid terpenoid catabolite that can able to activate a subset of Abscisic acid repectors. Phaseic acid is a plant hormone associated with photosynthesis arrest and abscission.
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DC72477 L-Tryptophanylglycine
L-Tryptophanylglycine (Trp-gly) is a dipeptide that can inhibit Ceronapril uptake by Caco-2 cells, with a Ki of 7.19 mM.
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DC72476 Indole-C2-amide-C2-NH2
Indole-C2-amide-C2-NH2 is a potent linker.
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DC72475 G0 N-glycan-Asn
G0 N-glycan-Asn is a glycopeptide. G0 N-glycan-Asn can be used for various biochemical studies.
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DC72474 Asobamast
Asobamast is a potent, orally active antiallergic agent that inhibits ige mediated passive pulmonary allergic responses in rats (ED50=4.7 mg/kg) and inhibits antigen-induced mediator release from sensitized guinea pig lung fragments.
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DC72473 2'-O-MB-cAMP sodium
2'-O-MB-cAMP (2'-O-Monobutyryl cyclic AM) sodium is an activatable prodrug of Cyclic AMP.
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DC72472 OSu-PEG4-VC-PAB-MMAE
OSu-PEG4-VC-PAB-MMAE involves in GDP-FAmP4MMAE (Monomethylauristatin E) synthesis, which is for GDP label via site-specific conjugation.
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DC72471 Sialylglyco peptide
Sialylglyco peptide is a N-Glycan and sialate glycopeptide.
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DC72470 Glp-Trp-OEt
Glp-Trp-OEt, a pyroglutamyl-tryptophan derivative, is a dipeptide Et ester.
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DC72469 Fmoc-EDA-N3
Fmoc-EDA-N3 is a click chemistry reagent containing an azide group.
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DC72468 DBCO-PEG2-NHS ester
DBCO-PEG2-NHS ester is a click chemistry reagent containing an azide group. DBCO-PEG2-NHS ester is a click chemistry PEG reagent containing NHS ester that is able to react specifically and efficiently with primary amines (e.g. the side chain of lysine residues or aminosilane-coated surfaces) at neutral or slightly basic condition to form a covalent bond. The hydrophilic PEG spacer arm improves water solubility and provides a long and flexible connection that minimizes steric hindrance involved with ligation. DBCO is commonly used for copper-free Click Chemistry reactions. Reagent grade, for research use only.
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DC72467 5-Oxoprolyltryptophan
5-Oxoprolyltryptophan is a model substrate for investigating the increase of serotonin at the cerebral level.
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DC72466 H-Cys-Val-2-Nal-Met-OH
H-Cys-Val-2-Nal-Met-OH is a peptide. H-Cys-Val-2-Nal-Met-OH is a peptidomimetic derivative that can be used to label short peptide sequences.
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DC72465 (R)-PF-04991532
(R)-PF-04991532 is the R-enantiomer of PF-04991532. PF-04991532 is a potent, hepatoselective glucokinase activator.
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DC72464 NCGC00138783 free base
NCGC00138783 free base is a selective inhibitor targeting CD47/SIRPα axis, with an IC50 of 50 µM. NCGC00138783 free base directly blocks the interaction between CD47 and SIRPα axis.
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DC72463 L1-PEG2-TATE
L1-PEG2-TATE is a nonadentate ligand. L1-PEG2-TATE can be used for the research of imaging.
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DC72462 JA-ACC
JA-ACC (Jasmonyl-ACC) is a derivative of 1-aminocyclopropane-1-carboxylic acid (ACC). is ACC is the direct precursor of the plant hormone ethylene. JA-ACC inhibits root growth in Arabidopsis and the inhibition is independent of jasmonic acid (JA) signaling.
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DC72461 Dihydrokalafungin
Dihydrokalafungin (Antibiotic YS-02931K-β) is a benzoisochromanequinone that used as a natural substrate in enzyme assays of the ActVB-ActVA system.
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DC72459 LSTc
LSTc (LS-tetrasaccharide c) is a human lactooligosaccharide presents on glycoproteins and glycolipids. LSTc is also a specific human JC polyomavirus (JCV) recognition motif. LSTc has good potential for the study of progressive multifocal leukoencephalopathy (PML).
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