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Cat. No. Product Name Field of Application Chemical Structure
DC44125 DMT-dC(bz) Phosphoramidite
DMT-dC(bz) Phosphoramidite is typically used in the synthesis of DNA.
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DC44123 RIPK3-IN-1
RIPK3-IN-1 is a RIPK3 type II DFG-out inhibitor with an IC50 of 9.1 nM. RIPK3-IN-1 inhibits RIPK1 and RIPK2 with IC50s of 5.5 and >10 μM. RIPK3-IN-1 is also a c-Met kinase inhibitor with an IC50 of 1.1 μM.
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DC44122 PAO-Nap
PAO-Nap is the modified PAO attached a naphthalimide fluorophore using aminocaproic acid as a linker. PAO induces oxidative stress-mediated apoptosis in HL-60 cells by selectively targeting thioredoxin reductase.
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DC44121 Melarsomine dihydrochloride
Melarsomine dihydrochloride is a trivalent arsenical compound used as an adulticide. Melarsomine dihydrochloride can be used for the reserach of canine heartworm disease and other helminth infections.
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DC44120 Melarsomine
Melarsomine is a trivalent arsenical compound used as an adulticide. Melarsomine can be used for the reserach of canine heartworm disease and other helminth infections.
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DC44119 Nevirapine-D4
Nevirapine-D4 is deuterium labeled Nevirapine. Nevirapine is a non-nucleoside inhibitor of HIV-1 reverse transcriptase used to treat and prevent HIV/AIDS; with a Ki of 270 μM.
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DC44118 Reverse transcriptase-IN-1
Reverse transcriptase-IN-1 (Compound 12z), a diarylbenzopyrimidine (DABP) analogue, is a potent, orally active HIV-1 nonnucleoside reverse transcriptase inhibitor. Reverse transcriptase-IN-1 has antiviral activity with EC50 values of 3.4 nM, 4.3 nM and 3.6 nM for HIV-1 IIIB, E138K and K103N mutants, respectively. Reverse transcriptase-IN-1 also has an IC50of 13.7 nM against HIV-1 reverse transcriptase enzyme.
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DC44117 HCV-IN-31
HCV-IN-31 (compound 4) is a HCV inhibitor, with an EC50/EC95 of 15.7 μM for HCV replicon.
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DC44116 HBV-IN-4
HBV-IN-4, a phthalazinone derivative, is a potent and orally active HBV DNA replication inhibitor with an IC50 of 14 nM. HBV-IN-4 induces the formation of genome-free capsids and has potent anti-HBV potencies.
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DC44115 1-Dodecylimidazole
1-Dodecylimidazole (N-Dodecylimidazole) is a lysosomotropic detergent and a cytotoxic agent. 1-Dodecylimidazole causes cell death by its acid-dependent accumulation in lysosomes, disruption of the lysosomal membrane, and releaseof cysteine proteases into the cytoplasm. 1-Dodecylimidazole has hypocholesterolaemic activity and broad-spectrum antifungal activity.
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DC44109 Bis-acrylate-PEG5
Bis-acrylate-PEG5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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DC44108 Benzyl-PEG7-t-butyl ester
Benzyl-PEG7-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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DC44107 BET bromodomain inhibitor 1
BET bromodomain inhibitor 1 is an orally active, selective bromodomain and extra-terminal (BET) bromodomain inhibitor with an IC50 of 2.6 nM for BRD4. BET bromodomain inhibitor 1 binds to BRD2(2), BRD3(2), BRD4(1), BRD4(2), and BRDT(2) with high affinities (Kd values of 1.3 nM, 1.0 nM, 3.0 nM, 1.6 nM, 2.1 nM, respectively). bromodomain inhibitor 1 has anti-cancer activity.
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DC44105 UZH1a
UZH1a is a potent and selective METTL3 inhibitor, with an IC50 of 280 nM. UZH1a can be used for epitranscriptomic modulation of cellular processes. UZH1a has antitumor activity. UZH1a also can be used as a chemical probe for studying METTL3.
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DC44104 Hydrazide-PEG4-Desthiobiotin
Hydrazide-PEG4-Desthiobiotin is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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DC44103 Benzyl-PEG7-azide
Benzyl-PEG7-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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DC44100 Benzyl-PEG6-azide
Benzyl-PEG6-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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DC44097 7-Iodo-7-deaza-2'-deoxyguanosine
7-Iodo-7-deaza-2'-deoxyguanosine (7-Deaza-7-Iodo-2'-deoxyguanosine) is a deoxyguanosine derivative that can be used in DNA synthesis and sequencing reactions.
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DC44096 Benzyl-PEG3-methyl ester
Benzyl-PEG3-methyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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DC44095 3-Aminophenol-PEG4-methyl
3-Aminophenol-PEG4-methyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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DC44094 2-Ethyl-6-methylphenol
2-Ethyl-6-methylphenol, alkylphenol, is isolated form the tumorigenic neutral subfraction of cigarette smoke condensate. 2-Ethyl-6-methylphenol exhibits insecticidal and bactericidal activities.
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DC44093 2,4-Dimethoxybenzyl alcohol
2,4-Dimethoxybenzyl alcohol, an aromatic alcohol, is a substrate of glucose-methanol-choline (GMC) oxidoreductase. GMC oxidoreductase displays the characteristics of an aryl-alcohol oxidase.
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DC44092 Benzyl-PEG2-ethanol
Benzyl-PEG2-ethanol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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DC44091 Endo-BCN-Nitrobenzene
Endo-BCN-Nitrobenzene is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs.
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DC44090 ddGTP
ddGTP (2',3'-Dideoxyguanosine 5'-triphosphate) is one of 2',3'-dideoxyribonucleoside 5'-triphosphates (ddNTPs) that acts as chain-elongating inhibitor of DNA polymerase for DNA sequencing.
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DC44089 FLT3-IN-4
FLT3-IN-4 is a potent and orally effective Fms-like tyrosine receptor kinase 3 (FLT3; IC50=7 nM) inhibitor for treating acute myelogenous leukemia.
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DC44088 rel-Zotatifin
rel-Zotatifin is the racemic isomer of Zotatifin, acts as an eIF4A inhibitor with activity less than Zotatifin. Zotatifin (eFT226) is a potent, selective, and well-tolerated eIF4A inhibitor. Zotatifin promotes eIF4A binding to specific mRNA sequences with recognition motifs in the 5’-UTRs (IC50=2 nM) and interferes with the assembly of the eIF4F initiation complex.
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DC44087 THP-PEG1-Boc
THP-PEG1-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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DC44086 Boc-C2-NH2
Boc-C2-NH2 is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs.
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DC44085 Acid-PEG2-ethyl propionate
Acid-PEG2-ethyl propionate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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