Novel potent anticancer agent, disturbing microtubule formation at the centrosomes and inhibiting the growth of tumors dose-dependently in the HCT116 human colon cancer xenograft model in vivo

Novel potent and selective CHEK2>Chk2 inhibitor

Novel Grp94-selective inhibitor PU-WS13 biotin probe

Natural heat shock protein 90 (Hsp90) inhibitor, potentiating the echinocandin drug caspofungin in caspofungin-resistant fungal pathogens, blocking the induction of caspofungin-responding genes required for the adaptation to cell wall stress through the c

Dual inhibitor of PDE3 and PDE4

Novel specific Hsp90b1 inhibitor

Hsp90α- and Hsp90ß-selective inhibitor

Novel specific inhibitor of tumor Hsp90

Hsp90α- and Hsp90ß-selective inhibitor

Novel thermally activated delayed fluorescence (TADF) molecule that exhibits high external quantum efficiency (EQE) in non-doped organic light-emitting diodes (OLEDs) at high luminescence

Novel PTEN-like mitochondrial phosphatase PTPMT1 inhibitor

Novel non-competitive potent and selective inhibitor of protein tyrosine phosphatase 1B (PTP1B)

Novel NIR fluorescent probe for the detection of Aβ oligomers

Unique promoter of SMN2 exon 7 splicing, acting by directly stimulating splicing of exon 7

Novel Potent Multi-target PTK Inhibitor for the Treatment of Idiopathic Pulmonary Fibrosis (IPF)

Novel Inhibitor of the PTK7/β-Catenin Interaction Targeting the Wnt Signaling Pathway in Colorectal Cancer

Novel Inhibitor of the PTK7/β-Catenin Interaction Targeting the Wnt Signaling Pathway in Colorectal Cancer

Novel Brk/PTK6 kinase inhibitor

Novel CFTR modulator, binding to the poly-r(C) binding protein 1 (PCBP1), showing an affinity for RNA-bound PCBP1 higher than that of free PCBP1

Novel CFTR modulator, increasing CFTR protein expression across different mutations, including F508del, by increasing CFTR mRNA levels by ~1.5 to ~2-fold in HBE cells

Natural antifungal agent, against postharvest fruit pathogenic fungi

Novel inhibitor of hypoxia-induced VEGF expression

Novel Bovine Viral Diarrhea (BVD) Inhibitor, specifically blocking BVDV cell entry

Na-K ATPase inhibitor, stimulating SERCA2a and accelerating calcium cycling in heart failure by relieving phospholamban inhibition

Novel PSMA ligand conjugated with fluorescent dye SulfoCy7, demonstrating good visualization of PSMA-expressing tumors and the absence of any explicit toxicity up to 87.9 mg/kg

Novel Highly Sensitive PSMA Probe for NIR-II Imaging and Intraoperative Tumor Resection, Visualizing Tumors in Real Time

Novel Selective, competitive GPR55 antagonist

Potent GPR55 antagonist

Novel Agonist of the Cannabinoid-Activated Orphan G-Protein-Coupled Receptor GPR18, being selective versus the CB-sensitive receptors CB1, CB2, and GPR55

Novel Agonist of the Cannabinoid-Activated Orphan G-Protein-Coupled Receptor GPR18, being selective versus the CB-sensitive receptors CB1, CB2, and GPR55