Cat. No. | Product Name | Field of Application | Chemical Structure |
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DC25013 | ARM-1 Featured |
A novel LTA4 hydrolase (LTA4H) inhibitor that inhibits LTB4 synthesis in human neutrophils with IC50 of 0.5 uM.
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DC22768 | MP07-66 Featured |
A novel FTY720 analog that acts as PP2A activator, disrupts the SET/PP2A interaction devoid of immunosuppressive effects leads to the reactivation of PP2A.
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DC32826 | AM-2232 Featured |
AM-2232 is a drug that acts as a potent but unselective agonist for the cannabinoid receptors.
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DC22223 | SB02024 Featured |
SB02024 is a novel highly potent, selective, ATP competitive, orally active inhibitor of vacuolar protein sorting 34 (Vps34) with Kd of 1 nM, >1000 times selective towards other PI3K isoenzymes; SB02024 is also highly selective at 1 uM in the DiscoveRx ScanMax panel of 468 kinases; reduces the number of GFP-2xFYVE puncta with IC50 of 14 nM, induces a dose-dependent increase in levels of NCOA4 and p62; blocks autophagy in vitro and reduces xenograft growth of two breast cancer cell lines, MDA-MB-231 and MCF-7; also significantly potentiates cytotoxicity of Sunitinib and Erlotinib in MCF-7 and MDA-MB-231 in vitro.
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DC20220 | MRS-1845 Featured |
MRS 1845 is a potent calcium channel protein inhibitor and inhibits capacitative Ca2+ influx in HL-60 cells (IC50 = 1.7 mM).
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DC21825 | Guanabenz Featured |
Guanabenz (WY 8678) is an α2 adrenergic receptor agonist that is used as an antihypertensive agent, also has been proposed to exert protective effects against misfolding by interfering with eIF2α-P dephosphorylation through selective disruption of a PP1-P
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DC10987 | LTX-315 |
This product is discontinued. LTX-315 (Oncopore) is a synthetic 9-mer anticancer peptide that preferentially permeabilizes mitochondrial membranes, thereby causing partially BAX/BAK1-regulated, caspase-independent necrosis.
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DC21325 | ML 792 Featured |
ML 792 is a potent, seletive SUMO-activating enzyme (SAE) inhibitor with IC50 of 3 nM and 11 nM for SAE/SUMO1 and SAE/SUMO2, respectively.
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DC11463 | Cruzain-IN-1(ML092) Featured |
ML092 is a covalent and reversible Cruzain inhibitor, with an IC50 of 10 nM.
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DC9820 | ML281 Featured |
ML281 is a potent and selective STK33 inhibitor with IC50 of 14 nM. ML281 showed a 550-fold selectivity over AurB and greater than 700-fold selectivity over PKA.
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DC7198 | MLN-120B Featured |
MLN120B is a potent and effective IKKbeta inhibitor.
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DC12496 | Mofezolac Featured |
Mofezolac is a Highly Selective Cyclooxygenase-1 Inhibitors,Counteracting Inflammatory State both In Vitro and In Vivo Models of Neuroinflammation.
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DC22320 | Mollugin Featured |
Mollugin is a JAK2 inhibitor and inhibits LPS-induced inflammatory responses by blocking the activation of the JAK-STAT pathway.
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DC7690 | MMAD Featured |
Monomethyl auristatin D (MMAD), a potent tubulin inhibitor, is a toxin payload in antibody drug conjugate.
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DC8339 | MPEP hydrochloride Featured |
MPEP is a potent, highly selective non-competitive antagonist at the mGlu5a receptor subtype (IC50 = 36 nM) while having no agonist or antagonist activities at the mGlu1b receptor at concentrations up to 30 μM.
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DC1015 | MPEP Featured |
MPEP is a selective mGlu5 receptor antagonist with IC50 of 36 nM.
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DC10894 | MSDC-0602 Featured |
MSDC-0602 is an insulin sensitizer potentially for the treatment of diabetes.
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DC20230 | mTOR inhibitor-1 Featured |
mTOR inhibitor-1 is a novel mTOR pathway inhibitor which can suppress cells proliferation and inducing autophagy.
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DC26051 | MX1013 Featured |
MX1013 is a dipeptide pan-caspase inhibitor that inhibits caspase-1
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DC8492 | Naloxegol Oxalate(NKTR-118) Featured |
Naloxegol is the first oral peripherally acting mu opioid receptor antagonists for opioid-induced constipation.
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DC8407 | Naloxone HCl Dihydrate Featured |
Naloxone HCl Dihydrate is an opioid inverse agonist drug used to counter the effects of opiate overdose.
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DC10551 | Necrostatin 2 racemate Featured |
Necrostatin 2 is a potent necroptosis inhibitor with EC50 of 50 nM.
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DC8290 | (S)-PFI-2 HCl Featured |
Negative control of (R)-PFI 2 hydrochloride. Exhibits 500-fold lower activity in a SETD7 enzymatic assay (IC50 = 1 μM) compared to the active enantiomer.
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DC23087 | Neoandrographolide Featured |
Neoandrographolide has antiradical, anti-inflammatory,and hypolipidemic effects, it protects the cardiovascular without significant liver damage. Neoandrographolide as chemosensitizer in S-Jurkat and X chromosome-linked inhibitor of apoptosis protein (XIA
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DC11281 | NGI-1 (ML414) Featured |
NGI-1 (ML414) is a potent, cell-permeable oligosaccharyltransferase (OST) inhibitor with IC50 of 1.1 uM.
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DC7758 | Nimorazole Featured |
Nimorazole is a nitroimidazole anti-infective.
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DC10549 | Nomifensine maleate Featured |
Nomifensine maleate is a selective inhibitor of dopamine uptake, used in adult attention deficit disorder.
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DC10453 | NP-118809 Featured |
NP-118809 is a N-type calcium channel blocker.
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DC9608 | NS-304(Selexipag) Featured |
NS-304(Selexipag; ACT-293987) is an oral, selective prostacyclin receptor agonist for the treatment of pulmonary arterial hypertension.
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DC10603 | NSC 247030(SU5201) Featured |
NSC 247030 is a bioactive chemical.
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